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phosphatidylethanolamine bioynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
phosphatidylserine + H+ <=> phosphatidylethanolamine + CO2 4.1.1.65 phosphatidylserine decarboxylase

S-adenosyl-L-methionine + phosphatidylethanolamine <=> phosphatidyl-N-methylethanolamine + S-adenosyl-L-homocysteine + H+ 2.1.1.17 phosphatidylethanolamine N-methyltransferase

ethanolamine + ATP <=> H+ + Phosphoethanolamine + ADP 2.7.1.32 choline kinase
2.7.1.82 ethanolamine kinase


S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine <=> phosphatidyl-N,N-dimethylethanolamine + H+ + S-adenosyl-L-homocysteine 2.1.1.103 phosphoethanolamine N-methyltransferase
2.1.1.16 methylene-fatty-acyl-phospholipid synthase
2.1.1.17 phosphatidylethanolamine N-methyltransferase
2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase




diacylglycerol + CDP-choline <=> phosphatidylcholine + CMP + H+ 2.7.8.1 ethanolaminephosphotransferase
2.7.8.2 diacylglycerol cholinephosphotransferase


diacylglycerol + CDP-ethanolamine <=> phosphatidylethanolamine + CMP + H+ 2.7.8.1 ethanolaminephosphotransferase
2.7.8.2 diacylglycerol cholinephosphotransferase


H+ + Phosphoethanolamine + CTP <=> CDP-ethanolamine + diphosphate 2.7.7.14 ethanolamine-phosphate cytidylyltransferase
2.7.7.15 choline-phosphate cytidylyltransferase


choline + ATP <=> H+ + phosphocholine + ADP 2.7.1.32 choline kinase
2.7.1.82 ethanolamine kinase


CDP-diacylglycerol + L-serine <=> CMP + phosphatidylserine + H+ 2.7.8.38 archaetidylserine synthase
2.7.8.8 CDP-diacylglycerol---serine O-phosphatidyltransferase


CTP + phosphocholine + H+ <=> CDP-choline + diphosphate 2.7.7.15 choline-phosphate cytidylyltransferase
2.7.7.57 N-methylphosphoethanolamine cytidylyltransferase


choline + CDP-diacylglycerol <=> phosphatidylcholine + CMP + H+ 2.7.8.24 phosphatidylcholine synthase

S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine <=> phosphatidylcholine + S-adenosyl-L-homocysteine + H+ 2.1.1.16 methylene-fatty-acyl-phospholipid synthase
2.1.1.17 phosphatidylethanolamine N-methyltransferase
2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase



choline <=> trimethylamine + acetaldehyde 4.3.99.4 choline trimethylamine-lyase

Visualization of the pathway